SCHEMBL6684465

SCHEMBL6684465

CCCC(=N)Nc1cc[nH]n1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CCNA1 P78396 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
ALDH1A1 P00352 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9140040 0.98 CCNA2 (0.33) CCNA2CDK2CCNA1GSK3AGSK3B
Hydrochloric Acid SCHEMBL9139780 0.84
SCHEMBL14324924 0.79 CCNA2 (0.52) CCNA2CDK2CCNA1GSK3AGSK3B
SCHEMBL9140019 0.77 GSK3A (0.34) CCNA2CDK2CCNA1GSK3AGSK3B
SCHEMBL4171832 0.76
Hydrochloric Acid SCHEMBL9138606 0.74
Iodide SCHEMBL2379375 0.73
SCHEMBL3077441 0.72
SCHEMBL4421326 0.71 LMNA (0.42) ALDH1A1ADORA3ADORA2AADORA1
Hydrochloric Acid SCHEMBL28556945 0.71 KLK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004072078-A1 PYRAZOLOTRIAZINE DERIVATIVES, METHODS FOR PRODUCTION AND USES THEREOF UNIVERSITE LOUIS PASTEUR (FR) 2004-08-26 WO disclosed