Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265041 | 0.86 | MEN1 (0.59) | MEN1KMT2AMAPTACP3MAOB | |
| SCHEMBL30412285 | 0.86 | MEN1 (0.59) | MEN1KMT2AMAPTACP3MAOB | |
| SCHEMBL2164148 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPTACP3EPHX1 | |
| Formaldehyde SCHEMBL9181082 | 0.83 | MEN1 (0.56) | MEN1KMT2AMAPTACP3MAOB | |
| SCHEMBL7640356 | 0.83 | MEN1 (0.56) | MEN1KMT2AMAPTACP3MAOB | |
| SCHEMBL10441255 | 0.82 | ACP3 (0.59) | MEN1KMT2AMAPTACP3MAOB | |
| SCHEMBL6865758 | 0.82 | MEN1 (0.62) | MEN1KMT2AMAPTACP3EPHX1 | |
| SCHEMBL11273244 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAPTACP3MAOB | |
| SCHEMBL11273245 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAPTACP3MAOB | |
| SCHEMBL11275212 | 0.82 | MEN1 (0.46) | MEN1KMT2AMAPTACP3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052280-A2 | ANTI-ANGIOGENIC COMPOUNDS AND THEIR USE IN CANCER TREATMENT | IMCLONE SYSTEMS INCORPORATED (US) | 2004-06-24 | — | — | WO | disclosed |