Sugi Predict

Sugi Predict / Compounds / SCHEMBL265041

SCHEMBL265041

SCHEMBL265041

CC(=O)Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ MAPT P10636 2/20 0.59
▸ ACP3 P15309 1/20 0.56
▸ MAOB P27338 2/20 0.55
▸ IDO1 P14902 2/20 0.54
▸ HTR2A P28223 1/20 0.53
▸ HTR2C P28335 1/20 0.53
▸ HTR2B P41595 1/20 0.53
▸ EPHX1 P07099 2/20 0.52
▸ TAAR1 Q96RJ0 1/20 0.51
▸ HDAC1 Q13547 2/20 0.51
▸ HDAC8 Q9BY41 2/20 0.51
▸ HTT P42858 2/20 0.51
▸ SMYD3 Q9H7B4 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ GFER P55789 1/20 0.51
▸ HDAC3 O15379 1/20 0.50
▸ HDAC4 P56524 1/20 0.50
▸ HDAC7 Q8WUI4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30412285 1.00 MEN1 (0.59) MEN1KMT2AMAPTACP3MAOB
Formaldehyde SCHEMBL9181082 0.97 MEN1 (0.56) MEN1KMT2AMAPTACP3MAOB
SCHEMBL21101909 0.88 CYP1A2 (0.50) MEN1KMT2AMAPTACP3MAOB
SCHEMBL11271901 0.87 MEN1 (0.57) MEN1KMT2AMAPTACP3MAOB
SCHEMBL6684469 0.86 MEN1 (0.56) MEN1KMT2AMAPTACP3MAOB
SCHEMBL10441255 0.85 ACP3 (0.59) MEN1KMT2AMAPTACP3MAOB
SCHEMBL6865758 0.85 MEN1 (0.62) MEN1KMT2AMAPTACP3IDO1
SCHEMBL29935522 0.84 MEN1 (0.65) MEN1KMT2AMAPTACP3EPHX1
SCHEMBL13547858 0.84 CYP1A2 (0.53) MEN1KMT2AMAPTHDAC8HDAC4
SCHEMBL11808569 0.84 MEN1 (0.60) MEN1KMT2AMAPTACP3IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4293009-B1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME ZOGENIX INTERNATIONAL LTD (GB) 2025-06-11 — — EP claimed
US-20240018090-A1 Processes for the Preparation of Fenfluramine THE BANK OF NOVA SCOTIA 2024-01-18 — — US claimed
EP-4293009-A2 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME Zogenix International Limited (GB) 2023-12-20 — — EP claimed
US-11634377-B2 Fenfluramine compositions and methods of preparing the same ZOGENIX INTERNATIONAL LIMITED (GB) 2023-04-25 — — US claimed
CN-113620901-B Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof 杭州师范大学 2023-02-10 — — CN claimed
CN-113499330-A Fenfluramine composition and preparation method thereof 周格尼克斯国际有限公司 2021-10-15 — — CN claimed
CN-108883399-B Fenfluramine composition and preparation method thereof 周格尼克斯国际有限公司 2021-06-22 — — CN claimed
US-20210147335-A1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME ZOGENIX INTERNATIONAL LIMITED (GB) 2021-05-20 — — US claimed
EP-3800177-A1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME Zogenix International Limited (GB) 2021-04-07 — — EP claimed
US-10947183-B2 Fenfluramine compositions and methods of preparing the same ZOGENIX INTERNATIONAL LIMITED (GB) 2021-03-16 — — US claimed
US-20110229808-A1 CURL-FREE IMAGING MEMBERS WITH A SLIPPERY SURFACE XEROX CORPORATION (US) 2011-09-22 — — US claimed
US-20110136049-A1 IMAGING MEMBERS COMPRISING FLUOROKETONE XEROX CORPORATION (US) 2011-06-09 — — US claimed
EP-1321455-B1 A process for the preparation of 1-(3-trifluoromethylphenyl)-2-(2-benzoyloxyethylamino)-propane SYNTECO SPA (IT) 2005-02-02 — — EP claimed
EP-1321455-A1 A process for the preparation of 1-(3-trifluoromethylphenyl)-2-(2-benzoyloxyethylamino)-propane Synteco S.p.A. (IT) 2003-06-25 — — EP claimed
EP-0875498-A2 Process for the production of the isomers (R) and (S)-Alpha-methyl-3-(trifluoromethyl)benzeneethanamine Alfa Chemicals Italiana S.r.l. (IT) 1998-11-04 — — EP claimed
US-5811586-A Process for manufacturing 1-(3-trifluoromethyl)-phenyl-propan-2-one intermediate in the synthesis of the fenfluramine ALFA CHEMICALS ITALIANA S.P.A. (IT) 1998-09-22 — — US claimed
US-5808156-A Process for the production of the isomers (R) and (S)-α-methyl-3(trifluoromethyl)benzeneethanamine ALFA CHEMICALS ITALIANA S.P.A. (IT) 1998-09-15 — — US claimed
EP-0810195-A1 Process for manufacturing 1-(3-trifluoromethyl)phenyl-propan-2-one intermediate in the synthesis of the fenfluramine ALFA CHEMICALS ITALIANA S.p.A. (IT) 1997-12-03 — — EP claimed
EP-0441160-B1 Process for preparing levo and dextro fenfluramine LAB MAG SPA (IT) 1995-07-05 — — EP claimed
EP-0441160-A1 Process for preparing levo and dextro fenfluramine LABORATORI MAG S.p.A. (IT) 1991-08-14 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147335-A1 FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME FAAH, FAAH2, TPH1 MEN1 2032/4885KMT2A 1462/4885MAPT 4001/4885
US-11634377-B2 Fenfluramine compositions and methods of preparing the same FAAH, FAAH2, TPH1 MEN1 2032/4885KMT2A 1462/4885MAPT 4001/4885
US-20240018090-A1 Processes for the Preparation of Fenfluramine PNMT, TPH2, CYP4F3 MEN1 2455/4885KMT2A 685/4885MAPT 2518/4885
US-10947183-B2 Fenfluramine compositions and methods of preparing the same FAAH, FAAH2, TPH1 MEN1 2032/4885KMT2A 1462/4885MAPT 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.