Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685135 | 0.83 | P2RY1 (0.36) | EPHX2RAB9ANPC1EPHX1P2RY1 | |
| SCHEMBL6682524 | 0.82 | EPHX2 (0.34) | EPHX2RAB9ANPC1EPHX1P2RY1 | |
| SCHEMBL6251538 | 0.82 | NPC1 (0.42) | EPHX2RAB9ANPC1EPHX1P2RY1 | |
| SCHEMBL6685856 | 0.81 | P2RY1 (0.36) | EPHX2RAB9ANPC1P2RY1PLA2G2A | |
| SCHEMBL6251451 | 0.79 | EPHX2 (0.49) | EPHX2RAB9ANPC1EPHX1P2RY1 | |
| SCHEMBL6252255 | 0.77 | P2RY1 (0.33) | EPHX2RAB9ANPC1EPHX1P2RY1 | |
| SCHEMBL6249425 | 0.75 | EPHX2 (0.54) | EPHX2RAB9ANPC1EPHX1 | |
| SCHEMBL6682615 | 0.74 | RAB9A (0.56) | RAB9ANPC1P2RY1KMT2AMEN1 | |
| SCHEMBL6687019 | 0.74 | NPC1 (0.40) | EPHX2RAB9ANPC1EPHX1P2RY1 | |
| SCHEMBL6251215 | 0.74 | EPHX2 (0.51) | EPHX2RAB9ANPC1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |