Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL18836924 | 0.87 | — | — | |
| Formic Acid SCHEMBL29929323 | 0.80 | — | — | |
| SCHEMBL28333523 | 0.79 | — | — | |
| SCHEMBL30581185 | 0.79 | — | — | |
| SCHEMBL4820393 | 0.79 | — | — | |
| SCHEMBL30581182 | 0.79 | — | — | |
| SCHEMBL1925147 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRNFKB1THPOHSD17B10 | |
| SCHEMBL1190178 | 0.79 | — | — | |
| SCHEMBL1332099 | 0.79 | — | — | |
| SCHEMBL2415 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818247-B1 | CAN INCLUDE AN ACTIVE AGENT SUCH AS ACTINOMYCIN D, PACLITAXEL, DOCETAXEL, OR RAPAMYCIN | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2004-11-16 | — | — | US | disclosed |