Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.60 |
| ▸ | CTSL | P07711 | 7/20 | 0.60 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5934876 | 1.00 | CTSK (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6685164 | 0.96 | CTSK (0.58) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5935088 | 0.96 | CTSK (0.58) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6687789 | 0.95 | CTSK (0.57) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5934875 | 0.95 | CTSK (0.57) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5935098 | 0.95 | CTSK (0.57) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5935001 | 0.95 | CTSK (0.56) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6693018 | 0.95 | CTSK (0.56) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6693027 | 0.95 | CTSK (0.56) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL5934862 | 0.93 | CTSK (0.61) | CTSKCTSLCTSBCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058238-A1 | USE OF CATHEPSIN K INHIBITORS FOR THE TREATMENT OF GLAUCOMA | ALCON, INC. (CH) | 2004-07-15 | — | — | WO | claimed |
| WO-2004058238-A1 | USE OF CATHEPSIN K INHIBITORS FOR THE TREATMENT OF GLAUCOMA | ALCON, INC. (CH) | 2004-07-15 | — | — | WO | disclosed |