SCHEMBL6684868

SCHEMBL6684868

CCC(Br)(Br)c1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CYP2A6 P11509 3/20 0.41
TSHR P16473 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 5/20 0.38
CYP2C19 P33261 3/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 2/20 0.38
HPGD P15428 2/20 0.37
CYP3A4 P08684 1/20 0.37
KEAP1 Q14145 1/20 0.37
ACP3 P15309 2/20 0.37
PTPN1 P18031 1/20 0.36
HPRT1 P00492 1/20 0.36
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6680536 0.84 ALDH1A1 (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL6680563 0.81 HTR1B (0.39) ALDH1A1CYP2A6TDP1CYP1A2CYP2C19
SCHEMBL6547735 0.81 ALDH1A1 (0.43) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL2127614 0.81 ALDH1A1 (0.43) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL6684965 0.80 CYP1A2 (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL6684254 0.80 KDM4E (0.38) ALDH1A1TDP1CYP1A2CYP2C19CYP2D6
SCHEMBL2875372 0.79 TP53 (0.35) ALDH1A1TSHRTDP1
SCHEMBL6547270 0.79 ALDH1A1 (0.41) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL2878043 0.79 HSD17B10 (0.39) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL6685429 0.78 KDM4E (0.39) ALDH1A1TDP1CYP1A2CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed