SCHEMBL6684873

SCHEMBL6684873

BrCC(Br)Cc1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.47
CYP1A2 P05177 3/20 0.47
CYP2C19 P33261 3/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2D6 P10635 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 1/20 0.43
ACP3 P15309 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
SLC6A4 P31645 1/20 0.41
MMP9 P14780 1/20 0.40
HPGD P15428 2/20 0.39
HTT P42858 1/20 0.39
CA2 P00918 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9252340 0.86 CYP1A2 (0.52) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6
SCHEMBL6680543 0.85 CTNNB1 (0.45) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6
SCHEMBL6680567 0.82 CTNNB1 (0.43) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6
SCHEMBL6684264 0.81 CTNNB1 (0.45) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6
SCHEMBL2875374 0.81 ALDH1A1 (0.33) CYP1A2ALDH1A1
SCHEMBL2878045 0.80 HSD17B10 (0.38) CYP1A2CYP2C19CYP2C9ALDH1A1TDP1
SCHEMBL18243140 0.80 CTNNB1 (0.54) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6
SCHEMBL7394253 0.80 CTNNB1 (0.54) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6
SCHEMBL6681399 0.80 CTNNB1 (0.44) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6
SCHEMBL6685436 0.80 CTNNB1 (0.44) CTNNB1CYP1A2CYP2C19CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed