⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175234 | 0.81 | TDP1 (0.46) | — | |
| SCHEMBL7613891 | 0.79 | KDM4E (0.42) | — | |
| SCHEMBL17540826 | 0.79 | KDM4E (0.42) | — | |
| Hydrochloric Acid SCHEMBL7609539 | 0.78 | KDM4E (0.41) | — | |
| SCHEMBL11419498 | 0.75 | — | — | |
| SCHEMBL1309431 | 0.75 | TDP1 (0.42) | — | |
| SCHEMBL1837224 | 0.75 | KDM4E (0.48) | — | |
| SCHEMBL6722276 | 0.73 | — | — | |
| SCHEMBL1155049 | 0.73 | — | — | |
| SCHEMBL27663 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420963-B2 | Rebamipide prodrugs, preparation method and use thereof | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2022-08-23 | — | — | US | disclosed |
| CN-108774277-B | Thiazole derivative containing glucosamine and coumarin molecules, and preparation method and application thereof | 淮海工学院 | 2021-12-21 | — | — | CN | disclosed |
| EP-2865669-B1 | NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF | SAMJIN PHARM CO LTD (KR) | 2021-04-28 | — | — | EP | disclosed |
| US-20150141409-A1 | NOVEL REVAMIPIDE PRODRUGS, PREPARATION METHOD AND USE THEREOF | ASTECH. CO., LTD. (KR) | 2015-05-21 | — | — | US | disclosed |
| EP-2865669-A1 | NOVEL REBAMIPIDE PRODRUG, METHOD FOR PRODUCING SAME, AND USAGE THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2015-04-29 | — | — | EP | disclosed |
| CN-100413867-C | 4-amino-5-phenyl-7-cyclohexyl-pyrrolo[2,3-d]pyrimidine derivatives | NOVARTIS AG (CH) | 2008-08-27 | — | — | CN | disclosed |
| CN-1711269-A | 4-amino-5-phenyl-7-cyclohexyl-pyrrolo[2,3-d]pyrimidine derivatives | NOVARTIS AG (CH) | 2005-12-21 | — | — | CN | disclosed |
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |
| US-4394520-A | SKIN DISORDERS | SOCIETE ANONYME DITE: L'OREAL (FR) | 1983-07-19 | — | — | US | disclosed |
| US-4204064-A | FOR TREATMENT OF SKIN OR SCALP | L'OREAL (FR) | 1980-05-20 | — | — | US | disclosed |
| US-4139635-A | Cysteamine derivatives for oral treatment of seborrhea | L'OREAL (FR) | 1979-02-13 | — | — | US | disclosed |
| US-4085217-A | DERIVATIVES OF CYSTEINE OR CYSTEAMINE | L'OREAL (FR) | 1978-04-18 | — | — | US | disclosed |
| US-4035492-A | Oral treatment of seborrhea with cysteamine derivatives | L'OREAL (FR) | 1977-07-12 | — | — | US | disclosed |
| US-3976781-A | SULFUR CONTAINING AMINES | L'OREAL (FR) | 1976-08-24 | — | — | US | disclosed |
| US-3950542-A | Cysteamine derivatives for oral treatment of seborrhea | L'OREAL (FR) | 1976-04-13 | — | — | US | disclosed |