SCHEMBL1155049

SCHEMBL1155049

NCCNC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL12469892 0.97
Bromide SCHEMBL3701110 0.97
SCHEMBL29270038 0.84 CA5B (0.55)
SCHEMBL11515499 0.84 CA5B (0.55)
SCHEMBL175234 0.83 TDP1 (0.46)
SCHEMBL3406422 0.82
SCHEMBL1332569 0.80
Monoethanolamine SCHEMBL6872043 0.80 ALDH1A1 (0.42)
SCHEMBL3281043 0.79
SCHEMBL6272996 0.78 PAOX (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108921-A Biocompatible and biostable polydimethylsiloxane polyurethane urea with chain extension of urea-based chain extender, preparation and application 北京理工大学 2024-05-31 CN claimed
EP-3898631-B1 NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS HOFFMANN LA ROCHE (CH) 2023-01-18 EP claimed
US-20230012368-A1 NOVEL IMIDAZOPYRAZINE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2023-01-12 US claimed
EP-3898631-A1 NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS F. Hoffmann-La Roche AG (CH) 2021-10-27 EP claimed
CN-113195497-A Novel imidazopyrazine derivatives 豪夫迈·罗氏有限公司 2021-07-30 CN claimed
WO-2020126953-A1 NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS F. HOFFMANN-LA ROCHE AG (CH) 2020-06-25 WO claimed
US-10414722-B2 Bioinspired catalysis using oligourea helical foldamers UREKA SARL (FR) 2019-09-17 US claimed
CN-102973520-A Diethylamide ethylenediamine compound-containing drug composition YAO YUN 2013-03-20 CN claimed
US-6649691-B2 Imidazolidone carbamate monomers made from vinyl ethylene carbonate reacted with N-aminoethylimidazolidone; emulsion polymerized with acrylate or vinyl acetate; coatings AIR PRODUCTS POLYMERS, L.P. 2003-11-18 US claimed
US-20030119982-A1 Wet adhesion monomer and derived copolymers for latex paints PINSCHMIDT ROBERT KRANTZ (US) 2003-06-26 US claimed
US-6538143-B1 Reaction product of vinyl ethylene carbonate, methacryloxypropylene carbonate, and allyloxypropylene carbonate; and alkyl or cyclic urea AIR PRODUCTS POLYMERS, L.P. 2003-03-25 US claimed
EP-1167356-A2 Wet adhesion monomer and derived copolymers for latex paints AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-01-02 EP claimed
US-4070317-A 5,5-DIALKYLHYDANTOIN, FORMALDEHYDE, SALICYLIC ACID AMIDE DEUTSCHE TEXACO AKTIENGESELLSCHAFT (DT) 1978-01-24 US claimed
JP-61044879-A None JP disclosed
US-20250043052-A1 PROCESS FOR PREPARING AN AQUEOUS POLYMER DISPERSION BASF SE (DE) 2025-02-06 US disclosed
US-20250042855-A1 PERIPHERALLY AND LUMINALLY-RESTRICTED INHIBITORS OF THE SEROTONIN TRANSPORTER AS TREATMENTS FOR DISORDERS OF GASTROINTESTINAL MOTILITY AND GUT-BRAIN AXIS THE JOHNS HOPKINS UNIVERSITY 2025-02-06 US disclosed
EP-0075827-A2 Polyepoxide curing by polymercaptans plus catalytic co-curing agents DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1983-04-06 EP disclosed
US-4251517-A FUNGICIDES CIBA-GEIGY CORPORATION (US) 1981-02-17 US disclosed
US-4131685-A ADRENERGIC BLOCKING AGENT, CARDIAC STIMULANT IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-12-26 US disclosed
US-4105417-A HYDROCARBYL PHENYL UREA, N-HYDROCARBYL ACETAMIDE OF ETHYLENEDIAMINE OR HYDROCARBYL-1-AMINOETHYL OXOIMIDAZOLIDONE COON MARVIN D 1978-08-08 US disclosed