Bicarbonate

Bicarbonate

SCHEMBL6685002

C/C=N/O.O=C(O)O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11218327 0.89
Acetic Acid SCHEMBL28584351 0.89
Carbamic Acid SCHEMBL2286984 0.86
Acetone SCHEMBL11226617 0.85
SCHEMBL202602 0.83
SCHEMBL93710 0.83
Glyoxylate SCHEMBL3379774 0.83
SCHEMBL114712 0.83
Urea SCHEMBL10348576 0.81
Hydrochloric Acid SCHEMBL20394242 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004502837-A 2004-01-29 JP claimed
US-6652970-B1 Stable after transformation 3M INNOVATIVE PROPERTIES COMPANY 2003-11-25 US claimed
EP-1301470-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M Innovative Properties Company (US) 2003-04-16 EP claimed
WO-2002004408-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO claimed
WO-2002004548-A1 POLYMER COMPOSITIONS WITH ENERGETICALLY DEGRADABLE CROSSLINKER 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO claimed
US-6652970-B1 Stable after transformation 3M INNOVATIVE PROPERTIES COMPANY 2003-11-25 US disclosed
EP-1301470-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M Innovative Properties Company (US) 2003-04-16 EP disclosed
US-6475316-B1 Methods of enhancing adhesion 3M INNOVATIVE PROPERTIES COMPANY 2002-11-05 US disclosed
WO-2002004408-A1 DEGRADABLE CROSSLINKERS, COMPOSITIONS THEREFROM, AND METHODS OF THEIR PREPARATION AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO disclosed
WO-2002004548-A1 POLYMER COMPOSITIONS WITH ENERGETICALLY DEGRADABLE CROSSLINKER 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO disclosed
WO-2002004550-A2 METHODS OF ENHANCING ADHESION 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-01-17 WO disclosed