SCHEMBL6685192

SCHEMBL6685192

N=C(N)C(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
EPHX1 P07099 2/20 0.50
SLC1A3 P43003 1/20 0.48
SLC1A2 P43004 1/20 0.48
SLC1A1 P43005 1/20 0.48
CPA3 P15088 3/20 0.48
CPA1 P15085 2/20 0.48
FOLH1 Q04609 1/20 0.48
CPB1 P15086 1/20 0.48
CPB2 Q96IY4 1/20 0.48
IDO1 P14902 3/20 0.48
NOS1 P29475 2/20 0.48
NOS3 P29474 1/20 0.48
NOS2 P35228 1/20 0.48
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
SLC6A2 P23975 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6831332 0.82 EPHX1 (0.50) CYP1A2EPHX1IDO1NOS1NOS3
SCHEMBL10425025 0.80 ALPI (0.61) EPHX1SLC1A3SLC1A2SLC1A1IDO1
SCHEMBL3110720 0.80 EPHX1 (0.48) CYP1A2EPHX1IDO1NOS1NOS3
SCHEMBL5052372 0.77 CYP1A2 (0.68) CYP1A2EPHX1SLC1A3SLC1A2SLC1A1
SCHEMBL6687587 0.77 ALPI (0.57) CYP1A2EPHX1SLC1A3SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL3666595 0.75 CYP1A2 (0.53) CYP1A2EPHX1SLC1A3SLC1A2SLC1A1
SCHEMBL21896194 0.74 TAAR1 (0.50) EPHX1IDO1NOS1NOS3NOS2
SCHEMBL7469503 0.74 EPHX1 (0.42) CYP1A2EPHX1IDO1NOS1NOS3
SCHEMBL3917090 0.74 EPHX1 (0.44) CYP1A2EPHX1SLC1A3SLC1A2SLC1A1
SCHEMBL6609906 0.72 CYP1A2 (0.61) CYP1A2EPHX1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed