SCHEMBL7469503

SCHEMBL7469503

C=CC(Cc1ccccc1)C(=N)N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.42
IDO1 P14902 3/20 0.41
NOS1 P29475 2/20 0.41
NOS3 P29474 1/20 0.41
NOS2 P35228 1/20 0.41
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
XIAP P98170 1/20 0.40
SLC7A5 Q01650 1/20 0.40
SLC6A2 P23975 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39
MAOA P21397 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2928010 0.77 CYP1A2 (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL3961925 0.77 CYP1A2 (0.55) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL9514047 0.76 CYP1A2 (0.53) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL9514042 0.74 CYP1A2 (0.47) EPHX1ALPIPKMPTGS1XIAP
SCHEMBL27814583 0.74 CTRB1 (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27418403 0.74 CYP1A2 (0.47) EPHX1ALPIPKMPTGS1XIAP
SCHEMBL6685192 0.74 CYP1A2 (0.56) EPHX1IDO1NOS1NOS3NOS2
SCHEMBL6831332 0.74 EPHX1 (0.50) EPHX1IDO1NOS1NOS3NOS2
SCHEMBL11088938 0.73 MDM2 (0.59) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL6845371 0.73 CYP1A2 (0.46) EPHX1ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250315-A1 FUNCTIONAL MONOMERS FOR MOLECULAR RECOGNITION AND CATALYSIS MIP Technologies AB (SE) 2002-10-23 EP disclosed
WO-2001055095-A1 FUNCTIONAL MONOMERS FOR MOLECULAR RECOGNITION AND CATALYSIS MIP TECHNOLOGIES AB (SE) 2001-08-02 WO disclosed