Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27943933 | 1.00 | CES2 (0.50) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL27383124 | 1.00 | CES2 (0.50) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL27925808 | 0.97 | CES2 (0.48) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL27944970 | 0.97 | CES2 (0.48) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL12099257 | 0.97 | CES2 (0.48) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL28392169 | 0.97 | CES2 (0.48) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL668240 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL27128353 | 0.95 | CES2 (0.43) | CES2CES1SMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL668274 | 0.92 | — | — | |
| SCHEMBL24684871 | 0.86 | KMT2A (0.36) | CES2CES1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107721996-A | A kind of preparation method and application of novel amino heterocyclic nitrogen compound | 河南龙湖生物技术有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-85106087-A | The synthesis technique of componds of substituted-formyl-anthracene cyclic esters | — | 1987-02-04 | — | — | CN | claimed |
| CN-118354796-A | Compounds, pharmaceutical compositions and methods for treating, preventing or managing hyperproliferative disorders | 文赛克斯制药有限责任公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-117813307-A | Difunctional degradants of interleukin-1 receptor related kinase and therapeutic uses thereof | 新锐思生物制药股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-111936468-B | Compounds with anticancer activity | 协和麒麟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-117425499-A | Methods of treating myotonic muscular dystrophy type 1 using peptide-oligonucleotide conjugates | 肽世代公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-117295525-A | Cell penetrating peptide conjugates and methods of use thereof | 牛津大学科技创新有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117157298-A | Dual-function chimeric heterocyclic compound of interleukin-1 receptor related kinase 4, preparation method, medicinal composition and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-114616239-B | Chimeric antigen receptor and T cell expressing chimeric antigen receptor therein | 北京门罗生物科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-113735978-B | Chimeric antigen receptor targeting CD19, preparation method and application thereof | 河北森朗生物科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116209658-A | Inhibitors of RHO-associated coiled coil kinase | 安吉昂生物医药公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2012023033-A2 | IMPROVED PEPTIDE IMMUNOGENS | PURDUE PHARMA L.P. (US) | 2012-02-23 | — | — | WO | disclosed |
| CN-101896183-A | Bicyclic amides for enhancing glutamatergic synaptic responses | CORTEX PHARMA INC | 2010-11-24 | — | — | CN | disclosed |
| CN-101862330-A | Bicyclic amide is used for the treatment of application in the medicament of respiration inhibition in preparation | CORTEX PHARMA INC | 2010-10-20 | — | — | CN | disclosed |
| US-20080199960-A1 | Methods for the Delivery of Oligomeric Compounds | K.U. LEUVEN RESEARCH AND DEVELOPMENT (BE) | 2008-08-21 | — | — | US | disclosed |
| WO-2005113571-A2 | METHODS FOR THE DELIVERY OF OLIGOMERIC COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-12-01 | — | — | WO | disclosed |
| EP-1147078-A1 | ACETYLENIC (BETA)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | American Cyanamid Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000044711-A1 | ACETYLENIC $G(b)-SULFONAMIDO AND PHOSPHINIC ACID AMIDE HYDROXAMIC ACID TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| CN-85105805-A | Produce the novel method of tricyclic quinoline derivatives | — | 1987-01-28 | — | — | CN | disclosed |
| US-3717548-A | METHOD FOR PREPARING AMINOCYCLOHEXYLPENICILLIN | KYOWA HAKKO KOGYO KK | 1973-02-20 | — | — | US | disclosed |