Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685476 | 1.00 | MAOB (0.47) | MAOBMAOACD274LMNAEGFR | |
| SCHEMBL6687637 | 0.91 | MAOB (0.57) | MAOBMAOAPOLBTP53MEN1 | |
| SCHEMBL6688726 | 0.90 | CD274 (0.45) | CD274LMNAPOLBSMN1; SMN2MEN1 | |
| SCHEMBL6688731 | 0.90 | CD274 (0.45) | CD274LMNAPOLBSMN1; SMN2MEN1 | |
| SCHEMBL6687664 | 0.89 | MAOB (0.59) | MAOBMAOACD274LMNAEGFR | |
| SCHEMBL6687667 | 0.89 | MAOB (0.59) | MAOBMAOACD274LMNAEGFR | |
| SCHEMBL6690944 | 0.88 | MAOB (0.48) | MAOBMAOACD274LMNAEGFR | |
| SCHEMBL6687864 | 0.87 | MAOB (0.45) | MAOBMAOACD274LMNAPARP15 | |
| SCHEMBL6687860 | 0.87 | MAOB (0.45) | MAOBMAOACD274LMNAPARP15 | |
| SCHEMBL6689256 | 0.84 | SCN9A (0.53) | MAOBMAOAPOLBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |