Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687864 | 0.94 | MAOB (0.45) | MAOBMAOACD274FFAR1ITGA4 | |
| SCHEMBL6687860 | 0.94 | MAOB (0.45) | MAOBMAOACD274FFAR1ITGA4 | |
| SCHEMBL6685101 | 0.91 | CD274 (0.45) | CD274ITGA4TP53ITGB1LMNA | |
| SCHEMBL6685099 | 0.91 | CD274 (0.45) | CD274ITGA4TP53ITGB1LMNA | |
| SCHEMBL6685482 | 0.88 | MAOB (0.47) | MAOBMAOACD274PARP15PARP10 | |
| SCHEMBL6685476 | 0.88 | MAOB (0.47) | MAOBMAOACD274PARP15PARP10 | |
| SCHEMBL6687664 | 0.86 | MAOB (0.59) | MAOBMAOACD274PARP15PARP10 | |
| SCHEMBL6687667 | 0.86 | MAOB (0.59) | MAOBMAOACD274PARP15PARP10 | |
| SCHEMBL6691050 | 0.85 | KMT2A (0.43) | MAOBMAOACD274ITGA4ITGB1 | |
| SCHEMBL6691044 | 0.85 | KMT2A (0.43) | MAOBMAOACD274ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |