Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CFD | P00746 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818577 | 0.83 | MAOB (0.65) | ALDH1A1HPGDMAPTKDM4EHTT | |
| SCHEMBL3628197 | 0.80 | SIRT2 (0.70) | ALDH1A1HPGDMAPTLMNAKDM4E | |
| SCHEMBL30311518 | 0.79 | HSD17B10 (0.63) | ALDH1A1HPGDKDM4EPOLBSIRT2 | |
| SCHEMBL2754257 | 0.79 | HSD17B10 (0.63) | ALDH1A1HPGDKDM4EPOLBSIRT2 | |
| SCHEMBL11374387 | 0.78 | ALDH1A1 (0.69) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8614489 | 0.78 | HPGD (0.71) | ALDH1A1HPGDMAPTLMNAKDM4E | |
| SCHEMBL6816841 | 0.77 | MAOB (0.69) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3353110 | 0.76 | KDM4E (0.66) | ALDH1A1HPGDMAPTLMNAKDM4E | |
| SCHEMBL11356477 | 0.76 | GAA (0.69) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL9728074 | 0.75 | ALDH1A1 (0.70) | ALDH1A1HPGDMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087685-A2 | PHOSPHOLIPASE C INHIBITORS FOR USE IN TREATING INFLAMMATORY DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-10-14 | — | — | WO | disclosed |