Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685555 | 1.00 | MAOB (0.56) | MAOBALDH1A1MAOASCN9AMME | |
| SCHEMBL6687173 | 0.86 | MAOB (0.65) | MAOBMAOASCN9AHRH3 | |
| SCHEMBL6687176 | 0.86 | MAOB (0.65) | MAOBMAOASCN9AHRH3 | |
| SCHEMBL17666278 | 0.86 | ALDH1A1 (0.58) | ALDH1A1SCN9A | |
| SCHEMBL6687904 | 0.84 | MAOB (0.56) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL6687900 | 0.84 | MAOB (0.56) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL6685585 | 0.84 | ATM (0.49) | ALDH1A1 | |
| SCHEMBL6685580 | 0.84 | ATM (0.49) | ALDH1A1 | |
| SCHEMBL6687209 | 0.83 | MAOB (0.55) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL6687215 | 0.83 | MAOB (0.55) | MAOBMMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |