Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685594 | 1.00 | SCN9A (0.50) | SCN9AMAOBMAOASCN3APPARA | |
| SCHEMBL8935445 | 0.84 | BCHE (0.55) | MEN1POLBMAPK1KMT2ANPSR1 | |
| SCHEMBL3291152 | 0.84 | BCHE (0.55) | MEN1POLBMAPK1KMT2ANPSR1 | |
| SCHEMBL3288931 | 0.84 | BCHE (0.55) | MEN1POLBMAPK1KMT2ANPSR1 | |
| SCHEMBL6691022 | 0.82 | MAOB (0.46) | SCN9AMAOBMAOAMEN1POLB | |
| SCHEMBL6691028 | 0.82 | MAOB (0.46) | SCN9AMAOBMAOAMEN1POLB | |
| SCHEMBL6688338 | 0.80 | MAOB (0.53) | MAOBPPARA | |
| SCHEMBL6688332 | 0.80 | MAOB (0.53) | MAOBPPARA | |
| SCHEMBL6688740 | 0.79 | SCN9A (0.77) | SCN9AMAOBMAOA | |
| SCHEMBL6688736 | 0.79 | SCN9A (0.77) | SCN9AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |