SCHEMBL6685618

SCHEMBL6685618

CC(C)(C)[Si](C)(C)OCCCCCCOC1(C(=O)O)C=CC(c2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.33
PPARG P37231 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4184936 0.82 PPARG (0.45) PPARG
SCHEMBL5828433 0.82 PPARG (0.45) PPARG
SCHEMBL11363522 0.82 PPARG (0.45) PPARG
SCHEMBL9462288 0.82 PPARG (0.45) PPARG
SCHEMBL4186205 0.82 PPARG (0.45) PPARG
SCHEMBL9489197 0.81 PARP1 (0.33) PPARG
SCHEMBL9490170 0.81 PARP1 (0.33) PPARG
SCHEMBL9487483 0.75 TSHR (0.44) PPARG
SCHEMBL9487207 0.75 TSHR (0.44) PPARG
SCHEMBL10442431 0.75 MAPT (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004083335-A2 GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME UNIVERSITY OF ROCHESTER (US) 2004-09-30 WO disclosed