Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 1.00 |
| ▸ | HRH1 | P35367 | 3/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219235 | 0.89 | HRH1 (0.80) | HRH3HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL11273968 | 0.88 | HRH1 (0.78) | HRH3HRH1DRD3 | |
| SCHEMBL11266451 | 0.85 | HRH1 (0.74) | HRH3HRH1KCNH2DRD3 | |
| SCHEMBL6071172 | 0.84 | HRH3 (0.79) | HRH3HRH1 | |
| SCHEMBL6071416 | 0.81 | HRH3 (0.69) | HRH3HRH1 | |
| SCHEMBL6071561 | 0.81 | HRH3 (0.88) | HRH3HRH1 | |
| SCHEMBL6071255 | 0.81 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL6690708 | 0.80 | HRH3 (0.79) | HRH3HRH1 | |
| SCHEMBL5100562 | 0.80 | HRH3 (0.79) | HRH3HRH1 | |
| SCHEMBL6071401 | 0.80 | HRH3 (1.00) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |