Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 17/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272047 | 0.80 | NOTUM (0.59) | NOTUMNPC1TP53MAPTRAB9A | |
| SCHEMBL2619231 | 0.78 | NOTUM (1.00) | NOTUMMAPT | |
| SCHEMBL6688366 | 0.76 | NOTUM (0.55) | NOTUMNPC1TP53MAPTRAB9A | |
| SCHEMBL6946139 | 0.76 | NOTUM (0.55) | NOTUMNPC1TP53MAPTRAB9A | |
| SCHEMBL16213753 | 0.75 | NOTUM (0.65) | NOTUMNPC1TP53MAPTRAB9A | |
| SCHEMBL3300297 | 0.75 | NOTUM (0.71) | NOTUM | |
| SCHEMBL18176101 | 0.73 | NOTUM (0.67) | NOTUMMAPTPKMCYP11B1CYP11B2 | |
| SCHEMBL1761149 | 0.71 | NOTUM (0.61) | NOTUMNPC1TP53MAPTRAB9A | |
| SCHEMBL6687673 | 0.71 | NOTUM (0.71) | NOTUM | |
| SCHEMBL4532424 | 0.71 | NOTUM (0.71) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085394-A1 | 7-NITROINDOLINE DERIVATIVES AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2004-10-07 | — | — | WO | disclosed |