Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 18/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300297 | 0.83 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL4532424 | 0.83 | NOTUM (0.71) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL2619231 | 0.83 | NOTUM (1.00) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL2611041 | 0.82 | NOTUM (0.65) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL24874051 | 0.81 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL1127318 | 0.81 | NOTUM (1.00) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL5765327 | 0.81 | NOTUM (1.00) | NOTUMCYP2D6CYP2C9 | |
| SCHEMBL5766165 | 0.81 | NOTUM (1.00) | NOTUMCYP2D6CYP2C9 | |
| SCHEMBL5803030 | 0.81 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL29862964 | 0.81 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085394-A1 | 7-NITROINDOLINE DERIVATIVES AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2004-10-07 | — | — | WO | disclosed |