Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685862 | 1.00 | MAOB (0.46) | MAOBSCN9AMAOACD274FFAR1 | |
| SCHEMBL6685304 | 0.89 | CD274 (0.42) | CD274FFAR1FFAR4PPARAPTPRZ1 | |
| SCHEMBL6685310 | 0.89 | CD274 (0.42) | CD274FFAR1FFAR4PPARAPTPRZ1 | |
| SCHEMBL6693062 | 0.89 | MAOB (0.45) | MAOBSCN9AMAOACD274FFAR4 | |
| SCHEMBL6693067 | 0.89 | MAOB (0.45) | MAOBSCN9AMAOACD274FFAR4 | |
| SCHEMBL6685530 | 0.85 | FFAR4 (0.48) | CD274FFAR1FFAR4PPARA | |
| SCHEMBL6685527 | 0.85 | FFAR4 (0.48) | CD274FFAR1FFAR4PPARA | |
| SCHEMBL6688691 | 0.85 | PDCD1 (0.44) | MAOBSCN9AMAOACD274 | |
| SCHEMBL6685877 | 0.84 | MAOB (0.61) | MAOBSCN9AMAOAPTPRZ1HRH3 | |
| SCHEMBL6685873 | 0.84 | MAOB (0.61) | MAOBSCN9AMAOAPTPRZ1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |