Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.42 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693062 | 1.00 | MAOB (0.45) | MAOBMAOASCN9AFFAR4NPC1 | |
| SCHEMBL6685506 | 0.89 | PDCD1 (0.53) | FFAR4NPC1PKMRAB9APDCD1 | |
| SCHEMBL6685503 | 0.89 | PDCD1 (0.53) | FFAR4NPC1PKMRAB9APDCD1 | |
| SCHEMBL6690103 | 0.89 | ATM (0.47) | FFAR4NPC1PKMRAB9APDCD1 | |
| SCHEMBL6690101 | 0.89 | ATM (0.47) | FFAR4NPC1PKMRAB9APDCD1 | |
| SCHEMBL6685289 | 0.89 | FFAR4 (0.43) | FFAR4NPC1PKMRAB9APDCD1 | |
| SCHEMBL6685286 | 0.89 | FFAR4 (0.43) | FFAR4NPC1PKMRAB9APDCD1 | |
| SCHEMBL6685862 | 0.89 | MAOB (0.46) | MAOBMAOASCN9AFFAR4CD274 | |
| SCHEMBL6685864 | 0.89 | MAOB (0.46) | MAOBMAOASCN9AFFAR4CD274 | |
| SCHEMBL6687571 | 0.87 | MAOB (0.47) | MAOBMAOASCN9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |