Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383257 | 0.87 | POLB (1.00) | POLBKMT2AMEN1S1PR3USP2 | |
| SCHEMBL7823011 | 0.83 | POLB (0.53) | POLBKMT2AMEN1MAPTHDAC3 | |
| SCHEMBL6780580 | 0.79 | POLB (0.76) | POLBKMT2AMEN1S1PR3USP2 | |
| SCHEMBL7657652 | 0.79 | POLB (0.76) | POLBKMT2AMEN1S1PR3USP2 | |
| SCHEMBL23715874 | 0.79 | POLB (0.76) | POLBKMT2AMEN1S1PR3USP2 | |
| SCHEMBL17664153 | 0.78 | POLB (0.69) | POLBKMT2AMEN1S1PR3USP2 | |
| SCHEMBL7651627 | 0.76 | POLB (0.76) | POLBKMT2AMEN1S1PR3USP2 | |
| SCHEMBL7680844 | 0.76 | POLB (0.51) | POLBKMT2AMEN1S1PR3MAPT | |
| SCHEMBL10954177 | 0.75 | POLB (0.76) | POLBKMT2AMEN1S1PR3USP2 | |
| SCHEMBL751586 | 0.75 | SMN1; SMN2 (0.74) | KMT2AMEN1MAPTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080389-A2 | HYDROXYEICOSADIENAMIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-09-23 | — | — | WO | disclosed |