SCHEMBL668628

SCHEMBL668628

Cc1cc(C)cc(C(=O)N(N)C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 0.46
TPMT P51580 1/20 0.45
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
HPGD P15428 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
C1S P09871 1/20 0.39
PRSS3 P35030 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoyl Chloride SCHEMBL8174019 0.83 ABCB1 (0.45) ABCB1TPMTCYP3A4CYP2C9CYP2C19
SCHEMBL8167532 0.82 HPGD (0.56) ABCB1CYP3A4CYP2C9CYP2C19HPGD
SCHEMBL9507319 0.80 ALDH1A1 (0.52) HTTHPGD
SCHEMBL667847 0.78 ABCB1 (0.40) ABCB1TPMTCYP3A4
SCHEMBL668765 0.77 CNR2 (0.43) ABCB1CYP3A4
SCHEMBL8082085 0.76 GPBAR1 (0.36) CYP3A4CYP2C9CYP2C19HTT
SCHEMBL10139314 0.76 ABCB1 (0.39) ABCB1TPMTCYP3A4HPGD
SCHEMBL20383955 0.74 TPMT (0.39) ABCB1TPMTCYP3A4CYP2C9CYP2C19
SCHEMBL27354891 0.74 TPMT (0.39) ABCB1TPMTCYP3A4CYP2C9CYP2C19
SCHEMBL418096 0.73 POLB (0.53) CYP3A4CYP2C9CYP2C19HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627678-A Synthesis process of methoxyfenozide 李德平 2019-12-31 CN claimed
JP-8081433-A None JP disclosed
US-10851119-B2 Boron-containing diacylhydrazines INTREXON CORPORATION (US) 2020-12-01 US disclosed
US-10851119-B2 Boron-containing diacylhydrazines INTREXON CORPORATION (US) 2020-12-01 US disclosed
US-20200157122-A1 BORON-CONTAINING DIACYLHYDRAZINES INTREXON CORP (US) 2020-05-21 US disclosed
US-20200157122-A1 BORON-CONTAINING DIACYLHYDRAZINES INTREXON CORP (US) 2020-05-21 US disclosed
EP-3194359-B1 BORON-CONTAINING DIACYLHYDRAZINE COMPOUNDS INTREXON CORP (US) 2020-04-08 EP disclosed
US-10570158-B2 Boron-containing diacylhydrazine compounds INTREXON CORPORATION (US) 2020-02-25 US disclosed
US-10570158-B2 Boron-containing diacylhydrazine compounds INTREXON CORPORATION (US) 2020-02-25 US disclosed
CN-110627678-A Synthesis process of methoxyfenozide 李德平 2019-12-31 CN disclosed
US-5530028-A CONTROLS INSECTS OF THE ORDER LEPIDOPTERA ROHM AND HAAS COMPANY (US) 1996-06-25 US disclosed
JP-H0881433-A INSECTICIDAL N,N'-DISUBSTITUTED-N,N'-DIACYL-HYDRAZINE ROHM & HAAS CO 1996-03-26 JP disclosed
EP-0693486-A1 Insecticidal N-substituted-N'-(optionally substituted)-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1996-01-24 EP disclosed
US-5482962-A Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1996-01-09 US disclosed
US-5424333-A Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines ROHM AND HAAS COMPANY (US) 1995-06-13 US disclosed
EP-0643040-A1 Amidrazones and their use as pesticides ROHM AND HAAS COMPANY (US) 1995-03-15 EP disclosed
US-5344958-A From 3-methoxy-2-(substituted)benzoic acid or ester ROHM AND HAAS COMPANY (US) 1994-09-06 US disclosed
EP-0602794-A2 Insecticidal N'-substituted-N, N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1994-06-22 EP disclosed
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed
EP-0236618-B1 INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10851119-B2 Boron-containing diacylhydrazines CD22, BRDT, BCR ABCB1 464/4885TPMT 4408/4885CYP3A4 3689/4885
US-20200157122-A1 BORON-CONTAINING DIACYLHYDRAZINES CD22, BRDT, BCR ABCB1 464/4885TPMT 4408/4885CYP3A4 3689/4885
US-10570158-B2 Boron-containing diacylhydrazine compounds BRDT, CD22, BCR ABCB1 279/4885TPMT 4166/4885CYP3A4 3536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.