SCHEMBL6686367

SCHEMBL6686367

CCC(O)c1ccc(Br)cc1

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.60
CXCR3 P49682 1/20 0.42
CYP1A2 P05177 1/20 0.42
IGF1R P08069 8/20 0.41
PGR P06401 1/20 0.41
HMOX1 P09601 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 1/20 0.40
SLC18A3 Q16572 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16479573 1.00 LMNA (0.60) LMNACXCR3CYP1A2IGF1RPGR
SCHEMBL1607138 0.87 LMNA (0.75) LMNACYP1A2PGRSLC6A2SLC6A3
SCHEMBL20639920 0.84 IGF1R (0.61) LMNAIGF1RMEN1KMT2A
SCHEMBL6111588 0.82 KMT2A (0.41) LMNACXCR3CYP1A2IGF1RHMOX1
SCHEMBL8077200 0.81 IGF1R (0.41) LMNACXCR3CYP1A2IGF1RHMOX1
SCHEMBL6686061 0.80 KDM4E (0.42) LMNACXCR3CYP1A2IGF1RHMOX1
SCHEMBL241160 0.80 IGF1R (0.43) CXCR3CYP1A2IGF1RHMOX1MEN1
SCHEMBL1986354 0.80 IGF1R (0.43) CXCR3CYP1A2IGF1RHMOX1MEN1
SCHEMBL2368070 0.80 IGF1R (0.43) CXCR3CYP1A2IGF1RHMOX1MEN1
SCHEMBL29861210 0.80 LMNA (0.65) LMNACYP1A2PGRSLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574033-A Phenylalanine derivative containing alkynyl and benzophenone groups and synthesis method 中国人民解放军军事科学院防化研究院 2023-08-11 CN claimed
CN-115074138-B Liquid crystal composition and liquid crystal display device 达兴材料股份有限公司 2024-11-19 CN disclosed
CN-118955244-A Method for preparing primary alcohol by homogeneously catalyzing and reducing carboxylic acid derivative by using N-heterocyclic carbene copper complex 延安大学 2024-11-15 CN disclosed
CN-118598898-A Synthetic method of non-natural alpha-amino acid derivative 华中科技大学 2024-09-06 CN disclosed
CN-118344244-A Preparation method of deuterated compound based on alkyl alcohol 大连理工大学 2024-07-16 CN disclosed
WO-2024067560-A1 SULFONAMIDE COMPOUND AND MEDICAL USE THEREOF 中国药科大学 2024-04-04 WO disclosed
CN-117682973-A Sulfonamide compound and medical application thereof 中国药科大学 2024-03-12 CN disclosed
CN-117682967-A Inhibitor for targeting c-Myc and application thereof 四川大学 2024-03-12 CN disclosed
CN-115215762-B Method for synthesizing aliphatic nitrile from alcohol 陕西师范大学 2024-02-02 CN disclosed
CN-115066423-B PD-L1 antagonist compounds 厦门宝太生物科技股份有限公司 2024-02-02 CN disclosed
WO-2009128559-A1 [1]BENZOTHIENO[3,2-B][1]BENZOTHIOPHENE COMPOUND AND METHOD FOR PRODUCING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME RICOH COMPANY, LTD. (JP) 2009-10-22 WO disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-1107944-A1 AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-06-20 EP disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
WO-2000012462-A1 AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-03-09 WO disclosed
EP-0354655-B1 1-PHENYL-1-PROPANOL DERIVATIVES CHISSO CORPORATION (JP) 1993-04-07 EP disclosed
US-5076947-A Optically active; free from temperature dependence CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0354655-A2 1-Phenyl-1-propanol derivatives CHISSO CORPORATION (JP) 1990-02-14 EP disclosed