Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109195 | 0.70 | TAAR1 (0.64) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL6687928 | 0.69 | SLC6A3 (0.47) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL4263561 | 0.69 | TRPV1 (0.48) | KDM4ETSHRMAPK1TRPV1 | |
| SCHEMBL28225467 | 0.68 | CYP3A4 (0.43) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL108109 | 0.68 | TAAR1 (0.62) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL28225686 | 0.68 | CYP3A4 (0.45) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL10136679 | 0.67 | CYP3A4 (0.64) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL16472966 | 0.67 | TSHR (0.62) | SLC6A4SLC6A2CYP2D6KDM4ETSHR | |
| SCHEMBL7741575 | 0.66 | TAAR1 (0.55) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 | |
| Machilin A SCHEMBL10343221 | 0.66 | TAAR1 (0.74) | TAAR1SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071481-A1 | MELANOGENESIS INHIBITOR AND SKIN PREPARATION CONTAINING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-08-26 | — | — | WO | disclosed |