Ethylenediamine

Ethylenediamine

SCHEMBL668649

NCCN.NCCN.NCCN.[Co]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.44
TSHR P16473 4/20 0.40
CA12 O43570 4/20 0.40
CA6 P23280 4/20 0.40
CA7 P43166 4/20 0.40
CA9 Q16790 4/20 0.40
CA14 Q9ULX7 4/20 0.40
CA5B Q9Y2D0 4/20 0.40
ALDH1A1 P00352 4/20 0.40
LMNA P02545 4/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA3 P07451 3/20 0.40
CA4 P22748 3/20 0.40
CA5A P35218 3/20 0.40
BLM P54132 2/20 0.40
DNM1 Q05193 1/20 0.40
CYP3A4 P08684 1/20 0.40
TDP1 Q9NUW8 4/20 0.36
MAPT P10636 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL1334048 1.00
Ethylenediamine SCHEMBL31422783 1.00
Ethylenediamine SCHEMBL948903 1.00
Ethylenediamine SCHEMBL27879448 0.93
Ethylenediamine SCHEMBL8726062 0.93 MAPT (0.46) NFKB1TSHRCA12CA6CA7
Ethylenediamine SCHEMBL23245690 0.93 MAPT (0.46) NFKB1TSHRCA12CA6CA7
Ethylenediamine SCHEMBL11315631 0.93
Ethylenediamine SCHEMBL8365876 0.93
Ethylenediamine SCHEMBL37647 0.91
Ethylenediamine SCHEMBL3083 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113522287-A Carbon-supported metal catalyst with hierarchical pore structure, preparation method and application thereof 中科合成油技术有限公司 2021-10-22 CN claimed
EP-3044329-B1 DEVICE PREPARATION USING CONDENSED NUCLEIC ACID PARTICLES LIFE TECHNOLOGIES CORP (US) 2020-04-22 EP claimed
CN-107754793-B Porous carbon loaded Fischer-Tropsch synthesis catalyst and preparation method and application thereof 中科合成油技术有限公司 2020-04-17 CN claimed
EP-2652052-B1 LIQUID ELECTROPHOTOGRAPHIC INK HEWLETT PACKARD DEVELOPMENT CO (US) 2016-09-07 EP claimed
EP-3044329-A1 DEVICE PREPARATION USING CONDENSED NUCLEIC ACID PARTICLES Life Technologies Corporation (US) 2016-07-20 EP claimed
WO-2015038954-A1 DEVICE PREPARATION USING CONDENSED NUCLEIC ACID PARTICLES Life Technologies Corporation (US) 2015-03-19 WO claimed
US-20120046471-A1 PROCESS FOR PREPARING ORGANIC COMPOUNDS BY A TRANSITION METAL-CATALYSED CROSS-COUPLING REACTION OF AN ARYL-X, HETEROARYL-X, CYCLOALKENYL-X OR ALKENYL-X COMPOUND WITH AN ALKYL, ALKENYL, CYCLOALKYL OR CYCLOALKENYL HALIDE SALTIGO GMBH (DE) 2012-02-23 US claimed
US-8030520-B2 Process for preparing organic compounds by a transition metal-catalysed cross-coupling reaction of an aryl-X, heteroaryl-X, cycloalkenyl-X or alkenyl-X compound with an alkyl, alkenyl, cycloalkyl or cycloalkenyl halide SALTIGO GMBH (DE) 2011-10-04 US claimed
US-20090247764-A1 PROCESS FOR PREPARING ORGANIC COMPOUNDS BY A TRANSITION METAL-CATALYSED CROSS-COUPLING REACTION OF AN ARYL-X, HETEROARYL-X, CYCLOALKENYL-X OR ALKENYL-X COMPOUND WITH AN ALKYL, ALKENYL, CYCLOALKYL OR CYCLOALKENYL HALIDE SALTIGO GMBH (DE) 2009-10-01 US claimed
US-6403343-B2 PLANT EXTRACT MITSUI CHEMICALS, INC. (JP) 2002-06-11 US claimed
EP-0683232-A1 PROCESS FOR PRODUCING TAXANE DITERPENE AND METHOD OF HARVESTING CULTRED CELL CAPABLE OF PRODUCING TAXANE DITERPENE IN HIGH YIELD MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-11-22 EP claimed
EP-0449969-B1 PHOTORESIST COMPOSITIONS CONTAINING COBALT (III) COMPOUND AND REDOX TRANSFER LIGAND EASTMAN KODAK CO (US) 1994-02-16 EP claimed
EP-0204526-B1 SILICONE ELASTOMERS XEROX CORPORATION (US) 1992-06-10 EP claimed
EP-0449969-A1 PHOTORESIST COMPOSITIONS CONTAINING COBALT (III) COMPOUND AND REDOX TRANSFER LIGAND. EASTMAN KODAK CO (US) 1991-10-09 EP claimed
US-4968586-A HIGH SPEED LITHOGRAPHIC PRINTING PLATES EASTMAN KODAK COMPANY (US) 1990-11-06 US claimed
WO-1990007730-A1 PHOTORESIST COMPOSITIONS CONTAINING COBALT (III) COMPOUND AND REDOX TRANSFER LIGAND EASTMAN KODAK COMPANY (US) 1990-07-12 WO claimed
US-4925895-A TRANSITION METAL COMPLEX FOR OXIDATION RESISTANCE, FUSER ROLLS IN ELECTROGRAPHIC MACHINES XEROX CORPORATION (US) 1990-05-15 US claimed
US-4777087-A MIXTURE OF POLYSILOXANE AND COMPLEX OF TRANSITION METAL SALT AND LIGAND XEROX CORPORATION (US) 1988-10-11 US claimed
EP-0204526-A2 Silicone elastomers XEROX CORPORATION (US) 1986-12-10 EP claimed
US-4615777-A Method and composition for reducing the voltage in an electrolytic cell OLIN CORPORATION (US) 1986-10-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247764-A1 PROCESS FOR PREPARING ORGANIC COMPOUNDS BY A TRANSITION METAL-CATALYSED CROSS-COUPLING REACTION OF AN ARYL-X, HETEROARYL-X, CYCLOALKENYL-X OR ALKENYL-X COMPOUND WITH AN ALKYL, ALKENYL, CYCLOALKYL OR CYCLOALKENYL HALIDE MLX, PYM1, CBR3 NFKB1 3620/4885TSHR 191/4885CA12 2471/4885
US-20120046471-A1 PROCESS FOR PREPARING ORGANIC COMPOUNDS BY A TRANSITION METAL-CATALYSED CROSS-COUPLING REACTION OF AN ARYL-X, HETEROARYL-X, CYCLOALKENYL-X OR ALKENYL-X COMPOUND WITH AN ALKYL, ALKENYL, CYCLOALKYL OR CYCLOALKENYL HALIDE TIMCC, ZFX, TSNAX NFKB1 2204/4885TSHR 526/4885CA12 4178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.