Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.40 |
| ▸ | CIT | O14578 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428876 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL8122592 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL9969913 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL15731847 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL8122591 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 | |
| Hydrochloric Acid SCHEMBL31251113 | 0.98 | DPP4 (0.43) | DPP4DPP8DPP9TERTDPP7 | |
| Hydrochloric Acid SCHEMBL31251112 | 0.98 | DPP4 (0.43) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL9650387 | 0.82 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL200229 | 0.82 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 | |
| SCHEMBL9650376 | 0.82 | DPP4 (0.44) | DPP4DPP8DPP9TERTDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013131018-A1 | BIARYL INHIBITORS OF THE SODIUM CHANNEL | ZALICUS PHARMACEUTICALS LTD. (US) | 2013-09-06 | — | — | WO | disclosed |
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |