SCHEMBL200229

SCHEMBL200229

CC[C@H](C)[C@H](N)C(=O)NO

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 12/20 0.44
DPP8 Q6V1X1 8/20 0.44
DPP9 Q86TI2 7/20 0.44
HDAC7 Q8WUI4 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TERT O14746 1/20 0.40
DPP7 Q9UHL4 7/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13887116 1.00 DPP4 (0.44) DPP4DPP8DPP9HDAC7HDAC8
SCHEMBL245069 1.00 DPP4 (0.44) DPP4DPP8DPP9HDAC7HDAC8
SCHEMBL9650376 0.82 DPP4 (0.44) DPP4DPP8DPP9CA1CA2
SCHEMBL8122592 0.82 DPP4 (0.44) DPP4DPP8DPP9TERTDPP7
SCHEMBL15731847 0.82 DPP4 (0.44) DPP4DPP8DPP9TERTDPP7
SCHEMBL8122591 0.82 DPP4 (0.44) DPP4DPP8DPP9TERTDPP7
SCHEMBL9650387 0.82 DPP4 (0.44) DPP4DPP8DPP9CA1CA2
SCHEMBL6686776 0.82 DPP4 (0.44) DPP4DPP8DPP9TERTDPP7
SCHEMBL9969913 0.82 DPP4 (0.44) DPP4DPP8DPP9TERTDPP7
SCHEMBL3661089 0.82 DPP4 (0.44) DPP4DPP8DPP9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 450 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3009504-B1 MICROORGANISM PRODUCING L-ISOLEUCINE AND METHOD FOR PREPARING L-ISOLEUCINE USING THE SAME CJ CHEILJEDANG CORP (KR) 2020-12-02 EP claimed
US-20160145699-A1 L-ISOLEUCINE-PRODUCING MICROORGANISM AND METHOD OF PRODUCING L-ISOLEUCINE USING THE SAME CJ CHEILJEDANG CORPORATION (KR) 2016-05-26 US claimed
EP-3009504-A1 MICROORGANISM PRODUCING L-ISOLEUCINE AND METHOD FOR PREPARING L-ISOLEUCINE USING SAME Cj Cheiljedang Corporation (KR) 2016-04-20 EP claimed
WO-2014200126-A1 MICROORGANISM PRODUCING L-ISOLEUCINE AND METHOD FOR PREPARING L-ISOLEUCINE USING SAME 씨제이제일제당 (주) (KR) 2014-12-18 WO claimed
US-20020076393-A1 Method for stimulation of defensin production MAGAININ PHARMACEUTICALS, INC. 2002-06-20 US claimed
WO-2001068085-A1 A METHOD FOR STIMULATION OF DEFENSIN PRODUCTION GENAERA CORPORATION (US) 2001-09-20 WO claimed
EP-1093364-A1 A METHOD FOR STIMULATION OF DEFENSIN PRODUCTION BY EXPOSURE TO ISOLEUCIN MAGAININ PHARMACEUTICALS INC. (US) 2001-04-25 EP claimed
WO-1999059574-A1 A METHOD FOR STIMULATION OF DEFENSIN PRODUCTION BY EXPOSURE TO ISOLEUCIN MAGAININ PHARMACEUTICALS, INC. (US) 1999-11-25 WO claimed
EP-0542487-A2 Process for producing L-isoleucine KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-05-19 EP claimed
JP-3112479-A None JP disclosed
JP-62198396-A None JP disclosed
US-12590128-B2 Acetohydroxy acid synthase variant and microorganism including the same CJ CHEILJEDANG CORPORATION (KR) 2026-03-31 US disclosed
US-12385074-B2 Method of producing L-amino acids AJINOMOTO CO., INC. (JP) 2025-08-12 US disclosed
EP-4505875-A1 METHOD FOR CONTROLLING PARASITIC PLANTS AJINOMOTO CO., INC. (JP) 2025-02-12 EP disclosed
EP-0131171-A1 Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of l-threonine and l-isoleucine AJINOMOTO CO., INC. (JP) 1985-01-16 EP disclosed
US-4442208-A GENETICALLY ENGINEERED CORYNEBACTERIUM OR BREVIBACTERIUM AJINOMOTO CO., INC. (JP) 1984-04-10 US disclosed
US-4411991-A MIXTURES, MICROORGANISMS, CARBOHYDRATES, LACTIC ACID, ONE STEP, AEROBIC KANEGAFUCHI CHEMICAL INDUSTRY COMPANY, LIMITED (JP) 1983-10-25 US disclosed
EP-0071023-A2 Method for producing L-isoleucine by fermentation AJINOMOTO CO., INC. (JP) 1983-02-09 EP disclosed
US-4329427-A BREVIBACTERIUM CULTURE W. R. GRACE & CO. (US) 1982-05-11 US disclosed
US-4183786-A FROM GYLCINE BY CULTURING MUTANT OF NOCARDIA KYOWA HAKKO KOGYO CO., LTD. (JP) 1980-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590128-B2 Acetohydroxy acid synthase variant and microorganism including the same ASNS, BCAT1, AARS1 DPP4 1644/4885DPP8 1092/4885DPP9 1757/4885
US-20020076393-A1 Method for stimulation of defensin production STING1, IFNG, TLR5 DPP4 420/4885DPP8 874/4885DPP9 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.