SCHEMBL6686848

SCHEMBL6686848

CCc1ccc(C(=O)c2cnc(OC)nc2OC)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TP53 P04637 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
THRB P10828 2/20 0.43
LMNA P02545 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
MAPT P10636 4/20 0.42
HTT P42858 1/20 0.42
PLK1 P53350 1/20 0.40
ACACB O00763 1/20 0.39
VNN1 O95497 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
RAB9A P51151 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
NPC1 O15118 1/20 0.38
ALOX15 P16050 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5376921 0.77 MAPT (0.44) ALDH1A1TP53SMN1; SMN2LMNAMAPT
SCHEMBL2745387 0.75 GAA (0.42) ALDH1A1NPSR1ACACBTDP1MEN1
SCHEMBL2745323 0.73 TDP1 (0.51) ALDH1A1SMN1; SMN2LMNAHTTACACB
SCHEMBL2759587 0.73 QPCT (0.52) ALDH1A1NPSR1ACACBMEN1KMT2A
SCHEMBL6691841 0.72 ACACB (0.38) ALDH1A1ACACBTDP1MEN1KMT2A
SCHEMBL3192298 0.71 NNMT (0.47) ALDH1A1ACACBTDP1
Lithium Ion SCHEMBL29595061 0.70 PLAU (0.39) ACACBTDP1
Lithium Ion SCHEMBL28621223 0.70 PLAU (0.39) ACACBTDP1
SCHEMBL29164644 0.69 PLAU (0.42) SMN1; SMN2ACACBTDP1MEN1KMT2A
SCHEMBL30822721 0.69 PLAU (0.42) SMN1; SMN2ACACBTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004099230-A1 MONOSACCHARIDE COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-11-18 WO disclosed