Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710096 | 0.85 | PPARG (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6255084 | 0.82 | — | — | |
| SCHEMBL7209110 | 0.81 | PDCD1 (0.35) | PDCD1CD274ADRB2 | |
| SCHEMBL5709182 | 0.79 | PDCD1 (0.34) | PDCD1CD274 | |
| SCHEMBL3163967 | 0.77 | BRD4 (0.33) | PDCD1CD274 | |
| SCHEMBL7930455 | 0.77 | BRD4 (0.33) | PDCD1CD274 | |
| SCHEMBL7202513 | 0.77 | PDCD1 (0.33) | PDCD1CD274 | |
| SCHEMBL7624920 | 0.76 | BCHE (0.33) | PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL8168468 | 0.76 | BRD4 (0.33) | PDCD1CD274 | |
| SCHEMBL8678769 | 0.76 | BRD4 (0.33) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257587-B1 | HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS | DOW GLOBAL TECHNOLOGIES INC (US) | 2004-06-23 | — | — | EP | claimed |
| US-6476283-B1 | Hydrogenation of unsaturated polymers using divalent diene-containing bis-cyclopentadienyl group IV metal catalysts | THE DOW CHEMICAL COMPANY | 2002-11-05 | — | — | US | claimed |
| US-6476283-B1 | Hydrogenation of unsaturated polymers using divalent diene-containing bis-cyclopentadienyl group IV metal catalysts | THE DOW CHEMICAL COMPANY | 2002-11-05 | — | — | US | disclosed |