Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | CPA2 | P48052 | 1/20 | 0.43 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687259 | 1.00 | ACE (0.52) | ACEERAP2ERAP1LNPEPDPP4 | |
| SCHEMBL6687452 | 1.00 | ACE (0.52) | ACEERAP2ERAP1LNPEPDPP4 | |
| SCHEMBL6692145 | 0.82 | DPP4 (0.62) | DPP4 | |
| SCHEMBL6685006 | 0.82 | DPP4 (0.62) | DPP4 | |
| SCHEMBL6685012 | 0.82 | DPP4 (0.62) | DPP4 | |
| SCHEMBL2177077 | 0.76 | DPP4 (0.57) | ACEDPP4NPC1RAB9ASPHK2 | |
| SCHEMBL474918 | 0.76 | DPP4 (0.57) | ACEDPP4NPC1RAB9ASPHK2 | |
| SCHEMBL449093 | 0.74 | DPP4 (0.58) | ACEDPP4F2NPC1RAB9A | |
| SCHEMBL4520158 | 0.74 | PRCP (0.65) | — | |
| SCHEMBL26616511 | 0.73 | PREP (0.60) | ACEDPP4F2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |