Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.62 |
| ▸ | PREP | P48147 | 6/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685012 | 1.00 | DPP4 (0.62) | DPP4PREPDPP8DPP7DPP9 | |
| SCHEMBL6685006 | 1.00 | DPP4 (0.62) | DPP4PREPDPP8DPP7DPP9 | |
| SCHEMBL6686205 | 0.84 | DPP4 (0.62) | DPP4PREPDPP8DPP7DPP9 | |
| SCHEMBL6692186 | 0.84 | DPP4 (0.62) | DPP4PREPDPP8DPP7DPP9 | |
| SCHEMBL6687259 | 0.82 | ACE (0.52) | DPP4 | |
| SCHEMBL6687254 | 0.82 | ACE (0.52) | DPP4 | |
| SCHEMBL6687452 | 0.82 | ACE (0.52) | DPP4 | |
| SCHEMBL6688921 | 0.75 | DPP4 (0.63) | DPP4PREPDPP8DPP7DPP9 | |
| SCHEMBL6686177 | 0.75 | DPP4 (0.55) | DPP4PREPDPP8DPP7 | |
| SCHEMBL6688053 | 0.74 | DPP4 (0.64) | DPP4PREPDPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |