Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687157 | 0.99 | PTGS1 (0.57) | PTGS1PTGS2MALT1L3MBTL1CCNB2 | |
| SCHEMBL6687131 | 0.95 | PTGS1 (0.60) | PTGS1PTGS2MALT1L3MBTL1MGLL | |
| SCHEMBL6687111 | 0.87 | PTGS1 (0.52) | PTGS1PTGS2MALT1L3MBTL1MGLL | |
| SCHEMBL6687447 | 0.84 | PTGS1 (0.57) | PTGS1PTGS2MALT1L3MBTL1MAPT | |
| SCHEMBL6681046 | 0.84 | PTGS2 (0.60) | PTGS1PTGS2MALT1L3MBTL1CNR1 | |
| SCHEMBL6686621 | 0.82 | PTGS1 (0.54) | PTGS1PTGS2MALT1L3MBTL1MGLL | |
| SCHEMBL6683372 | 0.79 | PTGS1 (0.69) | PTGS1PTGS2MALT1L3MBTL1ESR2 | |
| SCHEMBL6682126 | 0.78 | MALT1 (0.53) | PTGS1PTGS2MALT1L3MBTL1 | |
| SCHEMBL6132456 | 0.78 | PTGS2 (0.67) | PTGS1PTGS2MALT1L3MBTL1CNR1 | |
| SCHEMBL6684493 | 0.78 | PTGS1 (0.60) | PTGS1PTGS2MALT1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |