Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687421 | 1.00 | PPARG (0.63) | PPARGMEN1LMNAKMT2AALOX5 | |
| SCHEMBL6686210 | 0.85 | MEN1 (0.65) | PPARGMEN1LMNAKMT2AMAPT | |
| SCHEMBL6686213 | 0.85 | MEN1 (0.65) | PPARGMEN1LMNAKMT2AMAPT | |
| SCHEMBL6686570 | 0.83 | PPARG (0.86) | PPARGMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL6692673 | 0.83 | PPARG (0.86) | PPARGMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL6688926 | 0.82 | PPARG (0.67) | PPARGMEN1LMNAKMT2A | |
| SCHEMBL6688929 | 0.82 | PPARG (0.67) | PPARGMEN1LMNAKMT2A | |
| SCHEMBL6687446 | 0.80 | PPARG (0.67) | PPARGMEN1LMNAKMT2A | |
| SCHEMBL6687444 | 0.80 | PPARG (0.67) | PPARGMEN1LMNAKMT2A | |
| SCHEMBL6686162 | 0.79 | PPARG (0.77) | PPARGMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | disclosed |