Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692627 | 0.93 | MAPK1 (0.48) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6689603 | 0.92 | MAPK1 (0.48) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6683009 | 0.91 | MAPK1 (0.52) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6686093 | 0.89 | MAPK1 (0.52) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6678023 | 0.88 | MAPT (0.47) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6687978 | 0.88 | MAPT (0.47) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6684426 | 0.87 | MAPT (0.50) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6689377 | 0.87 | MAPT (0.50) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6688949 | 0.84 | MAPK1 (0.49) | MAPK1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6687647 | 0.84 | MAPT (0.54) | SMN1; SMN2MAPTALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |