Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20556888 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL27626690 | 0.88 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL27626827 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL27646900 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL3884493 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL2895314 | 0.79 | CYP3A4 (0.55) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL27626746 | 0.79 | ACE2 (0.36) | ALDH1A1TDP1CYP3A4OPRM1LMNA | |
| SCHEMBL27646931 | 0.79 | ALDH1A1 (0.34) | ALDH1A1TDP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL28836675 | 0.77 | CYP3A4 (0.53) | ALDH1A1TDP1CYP3A4TSHRCA2 | |
| SCHEMBL524297 | 0.77 | ALDH1A1 (0.65) | ALDH1A1TDP1CYP3A4TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1781955-A | Hydrogenation catalyst composition and method for hydrogenating conjugate diene polymer | TAIWAN RUBBER CO LTD (CN) | 2006-06-07 | — | — | CN | disclosed |
| EP-1189767-B1 | LOW ROLLING RESISTANCE TIRE FOR VEHICLES | PIRELLI (IT) | 2004-07-28 | — | — | EP | disclosed |
| EP-1189767-A1 | LOW ROLLING RESISTANCE TIRE FOR VEHICLES | PIRELLI PNEUMATICI Società per Azioni (IT) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000073092-A1 | LOW ROLLING RESISTANCE TIRE FOR VEHICLES | PIRELLI PNEUMATICI S.P.A. (IT) | 2000-12-07 | — | — | WO | disclosed |