Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.86 |
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681204 | 0.93 | MAPT (1.00) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22894160 | 0.93 | MAPT (1.00) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3911045 | 0.91 | MAPT (0.73) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6226359 | 0.91 | MAPT (0.73) | MAPTGAAALDH1A1NPC1RAB9A | |
| SCHEMBL1581519 | 0.88 | MAPT (0.69) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12720531 | 0.88 | MAPT (0.69) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31176219 | 0.88 | MAPT (0.69) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL10749962 | 0.88 | MAPT (0.69) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7223359 | 0.88 | MAPT (0.69) | MAPTGAAALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3259778 | 0.86 | MAPT (0.67) | MAPTGAAALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058982-A2 | ASYMMETRIC REDUCTIVE AMINATION OF KETONES | PENN STATE RESEARCH FOUNDATION (US) | 2004-07-15 | — | — | WO | disclosed |