Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6226359 | 0.93 | MAPT (0.73) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL6687730 | 0.91 | MAPT (0.86) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL31176219 | 0.90 | MAPT (0.69) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL8827999 | 0.90 | ALDH1A1 (0.63) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL11525907 | 0.85 | MAPT (0.83) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL5517703 | 0.85 | CHRM2 (0.66) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL11653014 | 0.84 | L3MBTL1 (0.86) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL6681204 | 0.84 | MAPT (1.00) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL22894160 | 0.84 | MAPT (1.00) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL26267962 | 0.84 | MAPT (0.76) | MAPTGAAL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-05-31 | — | — | US | disclosed |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-05-31 | — | — | US | disclosed |
| US-20200297607-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2020-09-24 | — | — | US | disclosed |
| US-20200297607-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2020-09-24 | — | — | US | disclosed |
| EP-3699250-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | Takasago International Corporation (JP) | 2020-08-26 | — | — | EP | disclosed |
| CN-111212884-A | Cold-sensitive composition containing 2,2, 6-trimethylcyclohexanecarboxylic acid derivative | 高砂香料工业株式会社 | 2020-05-29 | — | — | CN | disclosed |
| WO-2019078185-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | 高砂香料工業株式会社 | 2019-04-25 | — | — | WO | disclosed |
| WO-2019078185-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | 高砂香料工業株式会社 | 2019-04-25 | — | — | WO | disclosed |
| US-10035760-B2 | Inhibitors of human immunodeficiency virus replication | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2018-07-31 | — | — | US | disclosed |
| US-10035760-B2 | Inhibitors of human immunodeficiency virus replication | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2018-07-31 | — | — | US | disclosed |
| EP-2066601-A1 | HYDROSILYLATION | Agency for Science, Technology And Research (SG) | 2009-06-10 | — | — | EP | disclosed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2008039154-A1 | HYDROSILYLATION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-04-03 | — | — | WO | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| EP-1259475-A4 | TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS | UNIV YALE (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1259475-A1 | TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS | YALE UNIVERSITY (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064620-A1 | TRANSITION METAL-CATALYZED PROCESS FOR ADDITION OF AMINES TO CARBON-CARBON DOUBLE BONDS | YALE UNIVERSITY (US) | 2001-09-07 | — | — | WO | disclosed |
| US-5166350-A | Process for the manufacture of fluoran compounds | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| CN-87100686-A | 3-alkoxyl group-2-aminopropylamines as cardiovascular agents | — | 1987-10-14 | — | — | CN | disclosed |
| US-4067903-A | Manufacture of arylamines | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200297607-A1 | COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE | CNR2, ADRB2, TRPA1 | MAPT 1748/4885GAA 4870/4885L3MBTL1 3886/4885 |
| US-11344488-B2 | Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative | CNR2, ADRB2, TRPA1 | MAPT 1748/4885GAA 4870/4885L3MBTL1 3886/4885 |
| US-10035760-B2 | Inhibitors of human immunodeficiency virus replication | EIF2AK2, POLR1G, POLR1E | MAPT 2033/4885GAA 272/4885L3MBTL1 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.