Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29130862 | 0.85 | NOS1 (0.44) | NOS1NOS3NOS2 | |
| SCHEMBL13516847 | 0.85 | CYP2D6 (0.39) | NOS1NOS3NOS2CYP2D6HDAC3 | |
| SCHEMBL6684673 | 0.83 | CYP2D6 (0.49) | NOS1NOS3NOS2CYP2D6HDAC3 | |
| SCHEMBL9187786 | 0.83 | CYP2D6 (0.49) | NOS1NOS3NOS2CYP2D6HDAC3 | |
| SCHEMBL7328149 | 0.80 | CYP2D6 (0.49) | NOS1NOS3NOS2CYP2D6HDAC3 | |
| SCHEMBL18758702 | 0.80 | CYP2D6 (0.41) | NOS1NOS3NOS2CYP2D6HDAC3 | |
| SCHEMBL26113626 | 0.80 | NOS1 (0.43) | NOS1NOS3NOS2 | |
| SCHEMBL1934270 | 0.80 | CYP2D6 (0.41) | NOS1NOS3NOS2CYP2D6HDAC3 | |
| SCHEMBL21320780 | 0.80 | CYP2D6 (0.45) | NOS1NOS3NOS2CYP2D6HDAC3 | |
| SCHEMBL975517 | 0.80 | CYP2D6 (0.41) | NOS1NOS3NOS2CYP2D6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074336-A1 | NOVEL CATIONIC COPOLYMERS, USE THEREOF FOR THE VECTORISATION OF BIOMOLECULES AND SYNTHETIC INTERMEDIATES FOR THE SAME | HALISOL (FR) | 2004-09-02 | — | — | WO | disclosed |