Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254324 | 1.00 | SLC2A1 (0.49) | SLC2A1KCNH2JAK2JAK1KDM4D | |
| SCHEMBL3250355 | 1.00 | SLC2A1 (0.49) | SLC2A1KCNH2JAK2JAK1KDM4D | |
| SCHEMBL3254329 | 1.00 | SLC2A1 (0.49) | SLC2A1KCNH2JAK2JAK1KDM4D | |
| SCHEMBL3250358 | 1.00 | SLC2A1 (0.49) | SLC2A1KCNH2JAK2JAK1KDM4D | |
| SCHEMBL5726714 | 0.86 | SLC2A1 (0.61) | SLC2A1KCNH2 | |
| SCHEMBL5264092 | 0.83 | SLC2A1 (0.48) | SLC2A1KCNH2JAK2JAK1MAP4K4 | |
| SCHEMBL3249089 | 0.82 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3247718 | 0.82 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3250001 | 0.82 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3246385 | 0.82 | SLC2A1 (0.46) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470125-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064421-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |