Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3250001 | 1.00 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3246385 | 1.00 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3249089 | 1.00 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3254329 | 0.82 | SLC2A1 (0.49) | SLC2A1KCNH2 | |
| SCHEMBL6687899 | 0.82 | SLC2A1 (0.49) | SLC2A1KCNH2 | |
| SCHEMBL3250358 | 0.82 | SLC2A1 (0.49) | SLC2A1KCNH2 | |
| SCHEMBL3254324 | 0.82 | SLC2A1 (0.49) | SLC2A1KCNH2 | |
| SCHEMBL3250355 | 0.82 | SLC2A1 (0.49) | SLC2A1KCNH2 | |
| SCHEMBL5252383 | 0.82 | KCNH2 (0.60) | SLC2A1KCNH2 | |
| SCHEMBL5256971 | 0.82 | KCNH2 (0.60) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181996-A1 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2010-05-05 | — | — | EP | disclosed |
| US-7312212-B2 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2007-12-25 | — | — | US | disclosed |
| US-20050159411-A1 | Aminopiperidine derivatives | GLAXO GROUP LIMITED (GB) | 2005-07-21 | — | — | US | disclosed |
| EP-1470125-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064421-A1 | AMINOPIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159411-A1 | Aminopiperidine derivatives | AMPD2, AMPD3, NPEPPS | SLC2A1 3708/4885KCNH2 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.