Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480390 | 0.83 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2DPP4 | |
| SCHEMBL9369667 | 0.82 | SLC6A4 (0.53) | SLC6A4SLC6A3SLC6A2DPP4 | |
| Hydrochloric Acid SCHEMBL10669396 | 0.82 | SLC6A3 (0.77) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL25311594 | 0.80 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2DPP4 | |
| SCHEMBL13222778 | 0.78 | SLC6A2 (0.49) | SLC6A4SLC6A3SLC6A2DPP4HDAC4 | |
| SCHEMBL9098569 | 0.78 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2DPP4HDAC4 | |
| SCHEMBL12235288 | 0.77 | SLC6A3 (0.71) | SLC6A4SLC6A3SLC6A2 | |
| Hydrogen Peroxide SCHEMBL11527807 | 0.77 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2HDAC4 | |
| SCHEMBL8655542 | 0.75 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2HDAC4 | |
| SCHEMBL9841821 | 0.74 | SLC6A4 (0.53) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246793-B1 | SUBSTITUTED AMINOMETHYL-PHENYL-CYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-11-10 | — | — | EP | claimed |