Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806052 | 0.92 | TUBB1 (0.47) | TUBB1USP2L3MBTL1 | |
| SCHEMBL6672738 | 0.92 | TUBB1 (0.47) | TUBB1USP2L3MBTL1 | |
| SCHEMBL6675854 | 0.91 | TUBB1 (0.40) | TUBB1 | |
| SCHEMBL6688285 | 0.86 | TUBB1 (0.37) | TUBB1USP2 | |
| SCHEMBL6688291 | 0.86 | TUBB1 (0.37) | TUBB1USP2 | |
| SCHEMBL6671629 | 0.84 | TUBB1 (0.35) | TUBB1 | |
| SCHEMBL58323 | 0.80 | TUBB1 (0.53) | TUBB1 | |
| SCHEMBL89154 | 0.80 | TUBB1 (0.53) | TUBB1 | |
| SCHEMBL14568138 | 0.80 | TUBB1 (0.53) | TUBB1 | |
| SCHEMBL6671759 | 0.79 | TUBB1 (0.51) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |