Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CALML3 | P27482 | 1/20 | 0.31 |
| ▸ | SDHA | P31040 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046132 | 0.97 | MAOA (0.48) | MAOABACE1BACE2F10CYP11B1 | |
| SCHEMBL3041174 | 0.97 | MAOA (0.48) | MAOABACE1BACE2F10CYP11B1 | |
| SCHEMBL6671426 | 0.93 | MAOA (0.55) | MAOABACE1BACE2F10CYP11B1 | |
| SCHEMBL6671430 | 0.93 | MAOA (0.55) | MAOABACE1BACE2F10CYP11B1 | |
| SCHEMBL5999012 | 0.89 | MAOA (0.50) | MAOABACE1BACE2F10MAOB | |
| SCHEMBL3035482 | 0.86 | MAOA (0.59) | MAOAF10CYP11B1CYP11B2MAOB | |
| SCHEMBL3039436 | 0.85 | MAOA (0.46) | MAOAF10CYP11B1CYP11B2MAOB | |
| SCHEMBL3830925 | 0.84 | MAOA (0.49) | MAOABACE1BACE2F10MAOB | |
| SCHEMBL3830928 | 0.84 | MAOA (0.49) | MAOABACE1BACE2F10MAOB | |
| SCHEMBL27602211 | 0.79 | MAOA (0.39) | MAOACYP11B1CYP11B2MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072553-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |