Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967458 | 0.86 | MEN1 (0.55) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL11957019 | 0.84 | GRM5 (0.57) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL19046612 | 0.82 | GRM5 (0.58) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4312452 | 0.82 | GRM5 (0.51) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9180541 | 0.82 | GRM5 (0.53) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL20014800 | 0.82 | GRM5 (0.50) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL21384574 | 0.82 | TDP1 (0.50) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7517190 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2ASMN1; SMN2CYP2C19HTT | |
| SCHEMBL17886619 | 0.82 | GRM5 (0.55) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL12240997 | 0.82 | GRM5 (0.55) | GRM5MEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941998-B1 | 3,6-ketal macrolide antibiotics | PFIZER PROD INC (US) | 2004-09-01 | — | — | EP | disclosed |
| US-6043226-A | TREATING BACTERIAL, PARASITIC AND PROTOZOAL INFECTIONS | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0941998-A2 | 3,6-ketal and enol ether macrolide antibiotics | Pfizer Products Inc. (US) | 1999-09-15 | — | — | EP | disclosed |