Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GHSR | Q92847 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691753 | 1.00 | EPHX1 (0.63) | EPHX1TRPV1KMT2AMEN1GHSR | |
| SCHEMBL6688013 | 0.99 | EPHX1 (0.61) | EPHX1TRPV1KMT2AMEN1GHSR | |
| SCHEMBL6689821 | 0.89 | KMT2A (0.55) | EPHX1TRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6690836 | 0.89 | KMT2A (0.55) | EPHX1TRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6688083 | 0.89 | KMT2A (0.55) | EPHX1TRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6691686 | 0.87 | KMT2A (0.56) | EPHX1TRPV1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6689213 | 0.87 | KMT2A (0.56) | EPHX1TRPV1KMT2AMEN1EPHX2 | |
| SCHEMBL6693231 | 0.86 | KMT2A (0.53) | EPHX1TRPV1KMT2AMEN1GHSR | |
| SCHEMBL6692719 | 0.86 | KMT2A (0.56) | EPHX1KMT2AMEN1EPHX2ALDH1A1 | |
| SCHEMBL6694217 | 0.86 | LMNA (0.57) | EPHX1KMT2AMEN1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |